Table 4 Univariate-adjusted analysis for NASH vs Non-NASH NAFLD
From: The role of mitochondrial genomics in patients with non-alcoholic steatohepatitis (NASH)
Variable Name | Sample Size | P Value | Odds Ratio | Lower OR | Upper OR |
|---|---|---|---|---|---|
Age (yrs) | 247 | 0.106 | 1.02 | 1.00 | 1.04 |
BMI (kg/m2) | 244 | 0.173 | 1.02 | 0.99 | 1.05 |
WBC (x 103/uL) | 246 | 0.396 | 1.02 | 0.97 | 1.08 |
Platelet (x 103/ul) | 242 | 0.011 | 0.99 | 0.99 | 1.00 |
IR (HOMA) | 40 | 0.009 | 2.20 | 1.22 | 3.97 |
Glucose (mg/dL) | 232 | 0.068 | 1.01 | 1.00 | 1.01 |
ALT (U/L) | 245 | 0.000 | 1.03 | 1.02 | 1.05 |
AST (U/L) | 245 | 0.000 | 1.05 | 1.03 | 1.08 |
Triglycerides (mg/dL) | 219 | 0.127 | 1.00 | 1.00 | 1.01 |
LDL (mg/dL) | 193 | 0.854 | 1.00 | 0.99 | 1.01 |
Total Cholesterol (mg/dL) | 223 | 0.567 | 1.00 | 0.99 | 1.00 |
HDL (mg/dL) | 198 | 0.002 | 0.96 | 0.94 | 0.99 |
Male | 247 | 0.000 | 4.47 | 2.48 | 8.06 |
White | 247 | 0.639 | 1.16 | 0.62 | 2.18 |
Diabetes | 247 | 0.031 | 1.78 | 1.06 | 3.02 |
Hyperlipidemia | 237 | 0.144 | 1.47 | 0.88 | 2.49 |
Hypertension | 238 | 0.247 | 1.37 | 0.80 | 2.34 |
Haplotype, | |||||
 H | 247 | 0.566 | 0.86 | 0.51 | 1.45 |
 L | 247 | 0.023 | 0.34 | 0.13 | 0.86 |
 U | 247 | 0.128 | 1.80 | 0.84 | 3.84 |
 Other | 247 | 0.058 | 2.09 | 0.98 | 4.49 |
 K | 247 | 0.560 | 1.29 | 0.55 | 3.05 |
 J | 247 | 0.367 | 0.61 | 0.20 | 1.80 |
 T | 247 | 0.866 | 0.91 | 0.31 | 2.65 |
PNPLA3 SNP, | |||||
 CC | Reference | ||||
 GC | 247 | 0.000 | 2.90 | 1.67 | 5.05 |
 GG | 247 | 0.172 | 0.48 | 0.17 | 1.37 |