Fig. 2From: Validation of a high resolution NGS method for detecting spinal muscular atrophy carriers among phase 3 participants in the 1000 Genomes ProjectSimulation results of the number of SMN reads versus the posterior carrier probability for various levels of π for a maximum of (a) 3,000 and (b) 350 reads. Each point represents the average across 1,000 permutations. The red, blue, and green lines correspond to values of π less than or equal to 1/3 correspond to true carriersBack to article page