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Fig. 1 | BMC Medical Genetics

Fig. 1

From: SNP55, a new functional polymorphism of MDM2-P2 promoter, contributes to allele-specific expression of MDM2 in endometrial cancers

Fig. 1

Genomic organization of the human MDM2 gene. (a) The transcription start sites of the two promoters are indicated. (b) The two transcriptional products from the P1 and P2 promoters have different 5’ (untranslated region) UTR sequences. All MDM2 RNAs have the same 3’ UTR sequences, in which single nucleotide polymorphism (SNP) rs1690916 is located. SNP rs937283 is on exon 1, therefore only transcripts from the P1 promoter include this SNP

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BMC Medical Genetics

ISSN: 1471-2350

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