Table 6 Top 10 ranked SNPs in combining GEE association tests of fibrinogen levels measured at examination cycles 5, 6 and 7
SNP | MAF | CHR | Physical Position (bp)* | mean GEE P-value | Range of β Coefficients†(min, max) | Number of Phenotypes with GEE P-value < 0.01 | Gene within 60 Kb | GEE P-value of individual phenotypes | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | Â | Â | Â | Â | Exam 5 | Exam 6 | Exam 7 |
rs4861952 | 0.11 | 4 | 182,696,179.00 | 4.9 × 10-4 | -0.28 | -0.17 | 3 |  | 3.5 × 10-5 | 9.2 × 10-3 | 3.6 × 10-4 |
rs1869733 | 0.15 | 8 | 63,970,954.00 | 5.5 × 10-4 | -0.23 | -0.16 | 3 | FLJ39630 | 6.7 × 10-5 | 4.1 × 10-3 | 6.1 × 10-4 |
rs9317390 | 0.47 | 13 | 63,625,531.00 | 6.5 × 10-4 | 0.13 | 0.17 | 3 |  | 3.8 × 10-3 | 1.9 × 10-4 | 3.8 × 10-4 |
rs1561478 | 0.15 | 4 | 61,317,252.00 | 7.3 × 10-4 | 0.15 | 0.22 | 3 |  | 3.0 × 10-4 | 1.6 × 10-4 | 8.6 × 10-3 |
rs277330 | 0.16 | 5 | 53,489,351.00 | 1.1 × 10-3 | -0.22 | -0.16 | 3 | ARFRP2 | 1.5 × 10-3 | 1.9 × 10-4 | 4.1 × 10-3 |
rs1649053 | 0.41 | 10 | 59,991,493.00 | 1.2 × 10-3 | 0.13 | 0.18 | 3 |  | 2.8 × 10-3 | 5.8 × 10-3 | 1.0 × 10-4 |
rs2175271 | 0.09 | 15 | 34,097,057.00 | 1.5 × 10-3 | -0.26 | -0.20 | 3 |  | 6.5 × 10-3 | 3.1 × 10-4 | 1.8 × 10-3 |
rs9323656 | 0.06 | 14 | 77,394,323.00 | 1.5 × 10-3 | -0.31 | -0.27 | 3 | ADCK1; AK096919 | 1.2 × 10-3 | 2.5 × 10-3 | 1.3 × 10-3 |
rs1423741 | 0.42 | 16 | 59,874,592.00 | 1.8 × 10-3 | -0.17 | -0.11 | 3 |  | 7.6 × 10-4 | 9.4 × 10-3 | 7.6 × 10-4 |
rs10497881 | 0.32 | 2 | 205,818,470.00 | 2.2 × 10-3 | 0.14 | 0.17 | 3 | ALS2CR19 | 4.8 × 10-4 | 5.0 × 10-3 | 4.5 × 10-3 |