Table 2 Interaction of diabetes mellitus and E-selectin polymorphism in coronary artery disease

Interaction	Total	Controls n = 854	CAD n = 2224	odds ratio (95% C.I)	P value
No diabetes * S allele	422	256	166	Reference	-
No diabetes * R allele	44	24	20	1.28 [.69–2.4]	0.431
diabetes * S allele	2458	543	1915	5.44 [4.4–6.7]	< 0.001
diabetes * R allele	154	31	123	6.11 [3.9–9.5]	< 0.001

The data for the interaction between the S128R mutation and type 2 diabetes mellitus with regard to susceptibility of diabetic patients to acquiring coronary artery disease are presented in a 2 × 4 table. The four possible combinations of genotype and exposure are given in the first column of the table, and three categories of joint exposure are compared with the reference category of No diabetes * S allele.

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