| Original Sample | Follow-up Sample | Combined Sample |
---|
Pedigrees | 295 | 69a
| 352 |
Sibling-pairs | 629 | 102 | 753b
|
Patients | 695 | 141 | 836 |
Mean Onset ± SD | 39.3 ± 12.1 | 39.2 ± 11.8 | 39.3 ± 12.0 |
Mean HD repeat ± SD | 46.4 ± 5.9 | 45.5 ± 5.5 | 46.2 ± 5.7 |
- Note (details provided in Subjects section of Materials and Methods):
-
a57 pedigrees are newly recruited, and the remaining 12 are from the Original Sample with newly recruited siblings.
-
bThe number of pairs in the Combined Sample exceeds that for the sum of the Original Sample and Follow-up Sample because additional sibling pairs (21 new sibling pairs and one half sib) were created when new siblings were added to existing pedigrees.