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Table 2 Frequencies of HLA-A/B haplotypes in the two groups homozygous for H63D and C282Y in comparison with the control group.

From: HLA haplotypes associated with hemochromatosis mutations in the Spanish population

HAPLOTYPE

H63D HAPLOTYPES Freq (n = 276)

p

OR

C282Y HAPLOTYPES Freq (n = 200)

p

OR

CONTROLS Freq (n = 2226)

A1/B8

0.02513

N.S.

 

0.01500

N.S.

 

0.0246

A2/B7

0.03612

N.S.

 

0.02859

N.S.

 

0.0239

A2/B44

0.08254

N.S.

 

0.04037

N.S.

 

0.0443

A2/B51

0.04839

N.S.

 

0.00000

  

0.0404

A2/B35

0.01545

N.S.

 

0.03543

N.S.

 

0.0258

A3/B14

0.00000

  

0.00000

  

0.0005

A3/B7

0.00725

N.S.

 

0.20275

<10 -7

7.29

0.0343

A3/B62

0.00000

  

0.03379

10 -5

16.11

0.0024

A3/B44

0.00409

N.S.

 

0.08989

<10 -

12.13

0.0079

A11/B27

0.01812

N.S.

 

0.00000

  

0.0064

A11/B35

0.00362

N.S.

 

0.00862

N.S.

 

0.0204

A24/B35

0.00794

N.S.

 

0.01478

N.S.

 

0.0233

A29/B44

0.13261

<10 -7

3.93

0.02999

N.S.

 

0.0378

A29/B14

0.01449

<0.01

32.7

0.00000

  

0.0005

A29/B62

0.01591

<0.01

32.7

0.00000

  

0.0005

A30/B18

0.01087

N.S.

 

0.00000

  

0.0278

A33/B14

0.00000

  

0.00500

N.S.

 

0.0121

  1. Freq: Frequency n: Total number of haplotypes in each group OR: Odds ratio p: Significance level N.S.: Not significant