From: The impact of population heterogeneity on risk estimation in genetic counseling
 |  | AB NE(c) | AB E(d) | BB NE | |||
---|---|---|---|---|---|---|---|
rAB,NE (a) | rAB,E (b) | Relative risk | RMSE | Relative risk | RMSE | Relative risk | RMSE |
0.2 | 0.2 | 0.0127 | 0.0198 | 0.0135 | 0.0434 | 0.0099 | 0.0169 |
 | 0.4 | 0.0019 | 0.0191 | -0.0015 | 0.0472 | -0.0054 | 0.0162 |
 | 0.6 | -0.0060 | 0.0198 | -0.0094 | 0.0517 | 0.0135 | 0.0174 |
 | 0.8 | 0.0062 | 0.0204 | 0.0054 | 0.0613 | 0.0206 | 0.0169 |
0.6 | 0.2 | 0.0177 | 0.0257 | 0.0096 | 0.0454 | 0.0118 | 0.0169 |
 | 0.4 | 0.0109 | 0.0256 | -0.0049 | 0.0503 | -0.0014 | 0.0164 |
 | 0.6 | 0.0036 | 0.0266 | -0.0194 | 0.0545 | 0.0187 | 0.0174 |
 | 0.8 | 0.0155 | 0.0274 | -0.0095 | 0.0656 | 0.0281 | 0.0169 |
 |  | BB E | AA NE | AA E | |||
rAB,NE | rAB,E | Relative risk | RMSE | Relative risk | RMSE | Relative risk | RMSE |
0.2 | 0.2 | 0.0136 | 0.0376 | 0.0017 | 0.0395 | -0.0021 | 0.0690 |
 | 0.4 | -0.0063 | 0.0376 | -0.0010 | 0.0399 | -0.0104 | 0.0699 |
 | 0.6 | 0.0022 | 0.0383 | 0.0022 | 0.0394 | -0.0104 | 0.0720 |
 | 0.8 | 0.0115 | 0.0395 | 0.0081 | 0.0402 | -0.0087 | 0.0755 |
0.6 | 0.2 | 0.0182 | 0.0383 | 0.0024 | 0.0400 | -0.0014 | 0.0706 |
 | 0.4 | -0.0068 | 0.0377 | 0.0003 | 0.0399 | -0.0118 | 0.0714 |
 | 0.6 | -0.0025 | 0.0385 | 0.0044 | 0.0396 | -0.0150 | 0.0731 |
 | 0.8 | -0.0011 | 0.0390 | 0.0114 | 0.0402 | -0.0173 | 0.0744 |