Table 3 Association between SNPs with ischemic stroke using the additive, dominant, genotype, and the recessive models
From: Association between paraoxonase gene and stroke in the Han Chinese population
SNP | Model | Allele or geno | F_IS | Control | T-Statistic | Logistic Regression | ||
|---|---|---|---|---|---|---|---|---|
OR(95% CI) | P unadjusted | OR(95% CI) | P adjusted | |||||
rs854571 | Additive | C > T | 200/660 | 344/982 | 0.80(0.65-0.99) | 4.34E-02 | 0.84(0.66-1.07) | 1.62E-01 |
|  | Dominant | CC + CT/TT | 170/330 | 289/491 | 0.74(0.56-0.98) | 3.79E-02 | 0.80(0.58-1.10) | 1.63E-01 |
|  | Recessive | CC/CT + TT | 30/330 | 55/491 | 0.79(0.50-1.27) | 3.31E-01 | 0.82(0.49-1.37) | 4.45E-01 |
rs13306698 | Additive | A > G | 62/676 | 98/988 | 0.91(0.65-1.29) | 6.00E-01 | 1.07(0.72-1.59) | 7.43E-01 |
|  | Dominant | AA + AG/GG | 61/338 | 96/494 | 0.91(0.64-1.30) | 6.16E-01 | 1.09(0.72-1.64) | 6.83E-01 |
|  | Recessive | AA/AG + GG | 1/338 | 2/494 | 0.73(0.07-8.08) | 7.98E-01 | 0.55(0.04-7.85) | 6.63E-01 |
rs854572 | Additive | C > G | 285/668 | 413/964 | 0.99(0.82-1.21) | 9.44E-01 | 0.98(0.78-1.23) | 8.29E-01 |
|  | Dominant | CC + CG/GG | 220/334 | 324/482 | 0.94(0.70-1.27) | 6.87E-01 | 0.94(0.67-1.32) | 7.23E-01 |
|  | Recessive | CC/CG + GG | 65/334 | 89/482 | 1.07(0.75-1.52) | 7.21E-01 | 1.01(0.67-1.53) | 9.70E-01 |
rs7493 | Additive | C > G | 124/676 | 176/974 | 1.02(0.79-1.32) | 8.85E-01 | 0.98(0.73-1.31) | 8.82E-01 |
|  | Dominant | CC + CG/GG | 114/338 | 163/487 | 1.01(0.75-1.36) | 9.39E-01 | 0.99(0.71-1.39) | 9.68E-01 |
|  | Recessive | CC/CG + GG | 10/338 | 13/487 | 1.11(0.48-2.57) | 8.04E-01 | 0.85(0.34-2.12) | 7.23E-01 |
rs662 | Additive | G > A | 276/674 | 356/978 | 1.19(0.98-1.45) | 7.34E-02 | 1.18(0.94-1.47) | 1.46E-01 |
|  | Dominant | GG + GA/AA | 212/337 | 282/489 | 1.25(0.94-1.66) | 1.31E-01 | 1.20(0.86-1.66) | 2.84E-01 |
|  | Recessive | GG/GA + AA | 64/337 | 74/489 | 1.32(0.91-1.90) | 1.45E-01 | 1.35(0.88-2.06) | 1.67E-01 |
rs12026 | Additive | C > G | 124/672 | 174/978 | 1.05(0.81-1.36) | 7.26E-01 | 1.02(0.76-1.37) | 8.78E-01 |
|  | Dominant | CC + CG/GG | 114/336 | 162/389 | 1.04(0.77-1.39) | 8.11E-01 | 1.04(0.74-1.45) | 8.33E-01 |
|  | Recessive | CC/CG + GG | 10/336 | 12/489 | 1.22(0.52-2.86) | 6.48E-01 | 0.95(0.38-2.42) | 9.21E-01 |
rs1053275 | Additive | A > G | 144/666 | 186/994 | 1.19(0.94-1.52) | 1.51E-01 | 1.17(0.89-1.54) | 2.70E-01 |
|  | Dominant | AA + AG/GG | 129/333 | 165/497 | 1.27(0.95-1.70) | 1.02E-01 | 1.24(0.89-1.73) | 2.10E-01 |
|  | Recessive | AA/AG + GG | 15/333 | 21/497 | 1.07(0.54-2.11) | 8.47E-01 | 1.07(0.49-2.31) | 8.68E-01 |
rs705381 | Additive | G > A | 74/660 | 151/990 | 0.70(0.52-0.95) | 2.02E-02 | 0.65(0.47-0.92) | 1.35E-02 |
|  | Dominant | GG + GA/AA | 65/330 | 144/395 | 0.60(0.43-0.83) | 2.50E-03* | 0.54(0.37-0.79) | 1.67E-03* |
|  | Recessive | GG/GA + AA | 9/330 | 7/495 | 1.96(0.72-5.30) | 1.88E-01 | 1.85(0.60-5.64) | 2.83E-01 |
rs2074353 | Additive | A > G | 176/662 | 230/982 | 1.18(0.94-1.47) | 1.53E-01 | 1.23(0.95-1.60) | 1.09E-01 |
|  | Dominant | AA + AG/GG | 153/331 | 197/491 | 1.28(0.97-1.70) | 8.30E-02 | 1.38(1.00-1.91) | 5.29E-02 |
|  | Recessive | AA/AG + GG | 23/331 | 33/491 | 1.04(0.60-1.80) | 8.99E-01 | 1.06(0.56-1.99) | 8.69E-01 |
rs854560 | Additive | A > T | 30/674 | 39/996 | 1.14(0.70-1.85) | 5.93E-01 | 1.19(0.69-2.07) | 5.36E-01 |
|  | Dominant | AA + AT/TT | 29/337 | 38/498 | 1.14(0.69-1.89) | 6.11E-01 | 1.24(0.70-2.21) | 4.57E-01 |
|  | Recessive | AA/AT + TT | 1/337 | 1/498 | 1.48(0.09-23.73) | 7.82E-01 | 0.43(0.02-9.62) | 5.92E-01 |