Table 2 Association between SNPs and total stroke using the additive, dominant, genotype, and the recessive models
From: Association between paraoxonase gene and stroke in the Han Chinese population
SNP | Model | Allele or geno | F_Stroke | F_Control | T-Statistic | Logistic Regression | ||
|---|---|---|---|---|---|---|---|---|
OR(95% CI) | P unadjusted | OR(95% CI) | P adjusted | |||||
rs854571 | Additive | C > T | 298/992 | 344/982 | 0.79(0.65-0.96) | 1.71E-02 | 0.80(0.65-0.98) | 3.30E-02 |
|  | Dominant | CC + CT/TT | 253/496 | 289/491 | 0.73(0.57-0.94) | 1.33E-02 | 0.75(0.57-0.99) | 3.96E-02 |
|  | Recessive | CC/CT + TT | 45/496 | 55/491 | 0.79(0.52-1.20) | 2.69E-01 | 0.75(0.48-1.17) | 2.06E-01 |
rs13306698 | Additive | A > G | 98/1016 | 98/988 | 0.97(0.71-1.31) | 8.31E-01 | 1.00(0.71-1.40) | 9.99E-01 |
|  | Dominant | AA + AG/GG | 97/508 | 96/494 | 0.98(0.71-1.34) | 8.92E-01 | 1.02(0.72-1.44) | 9.20E-01 |
|  | Recessive | AA/AG + GG | 1/508 | 2/494 | 0.49(0.04-5.37) | 5.55E-01 | 0.39(0.03-5.06) | 4.74E-01 |
rs854572 | Additive | C > G | 443/1004 | 413/964 | 1.05(0.88-1.26) | 5.69E-01 | 1.09(0.89-1.32) | 4.08E-01 |
|  | Dominant | CC + CG/GG | 343/502 | 324/482 | 1.05(0.81-1.38) | 7.10E-01 | 1.11(0.82-1.48) | 5.04E-01 |
|  | Recessive | CC/CG + GG | 100/502 | 89/482 | 1.10(0.80-1.51) | 5.62E-01 | 1.13(0.80-1.61) | 4.93E-01 |
rs7493 | Additive | C > G | 192/1016 | 176/974 | 1.06(0.84-1.33) | 6.32E-01 | 1.00(0.78-1.29) | 9.89E-01 |
|  | Dominant | CC + CG/GG | 173/508 | 163/487 | 1.03(0.79-1.34) | 8.45E-01 | 1.00(0.75-1.34) | 9.85E-01 |
|  | Recessive | CC/CG + GG | 19/508 | 13/487 | 1.42(0.69-2.90) | 3.41E-01 | 1.00(0.46-2.18) | 9.93E-01 |
rs662 | Additive | G > A | 389/1014 | 356/978 | 1.08(0.91-1.29) | 3.86E-01 | 1.05(0.87-1.28) | 5.93E-01 |
|  | Dominant | GG + GA/AA | 303/507 | 282/489 | 1.09(0.85-1.40) | 5.02E-01 | 1.05(0.80-1.39) | 7.31E-01 |
|  | Recessive | GG/GA + AA | 86/507 | 74/489 | 1.15(0.82-1.61) | 4.32E-01 | 1.12(0.77-1.62) | 5.65E-01 |
rs12026 | Additive | C > G | 192/1010 | 174/978 | 1.09(0.86-1.37) | 4.80E-01 | 1.05(0.81-1.35) | 7.17E-01 |
|  | Dominant | CC + CG/GG | 173/505 | 162/489 | 1.05(0.81-1.37) | 7.07E-01 | 1.05(0.78-1.40) | 7.56E-01 |
|  | Recessive | CC/CG + GG | 19/505 | 12/489 | 1.55(0.75-3.24) | 2.39E-01 | 1.13(0.51-2.50) | 7.72E-01 |
rs1053275 | Additive | A > G | 203/1000 | 186/994 | 1.10(0.89-1.37) | 3.82E-01 | 1.10(0.86-1.39) | 4.53E-01 |
|  | Dominant | AA + AG/GG | 179/500 | 165/497 | 1.12(0.86-1.46) | 3.88E-01 | 1.13(0.85-1.51) | 3.90E-01 |
|  | Recessive | AA/AG + GG | 24/500 | 21/497 | 1.14(0.63-2.08) | 6.62E-01 | 1.04(0.54-1.99) | 9.17E-01 |
rs705381 | Additive | G > A | 106/988 | 151/990 | 0.67(0.51-0.87) | 3.13E-03* | 0.67(0.50-0.89) | 5.80E-03* |
|  | Dominant | GG + GA/AA | 95/494 | 144/495 | 0.58(0.43-0.78) | 3.20E-04* | 0.57(0.41-0.79) | 7.10E-04* |
|  | Recessive | GG/GA + AA | 11/494 | 7/495 | 1.59(0.61-4.13) | 3.43E-01 | 1.64(0.58-4.61) | 3.52E-01 |
rs2074353 | Additive | A > G | 253/996 | 230/982 | 1.11(0.91-1.36) | 3.16E-01 | 1.12(0.90-1.40) | 3.09E-01 |
|  | Dominant | AA + AG/GG | 219/498 | 197/491 | 1.17(0.91-1.51) | 2.20E-01 | 1.23(0.93-1.62) | 1.46E-01 |
|  | Recessive | AA/AG + GG | 34/498 | 33/491 | 1.02(0.62-1.67) | 9.47E-01 | 0.91(0.53-1.57) | 7.31E-01 |
rs854560 | Additive | A > T | 41/1014 | 39/996 | 1.03(0.66-1.61) | 8.84E-01 | 0.95(0.58-1.56) | 8.37E-01 |
|  | Dominant | AA + AT/TT | 40/507 | 38/498 | 1.04(0.65-1.65) | 8.78E-01 | 0.97(0.58-1.62) | 9.12E-01 |
|  | Recessive | AA/AT + TT | 1/507 | 1/498 | 0.98(0.06-15.75) | 9.90E-01 | 0.40(0.02-7.40) | 5.39E-01 |