Figure 1

Linkage disequilibrium (LD) plot across AGPAT6 . The box at the top shows the AGPAT6 gene with the location of the 28 SNPs included in this study. The 11 tag SNPs are indicated by circles around the rs number of the SNPs. The LD plot is based on the measure of D’. Each diamond indicates the pair wise magnitude of LD, with dark grey diamonds indicating strong LD (D’ > 0.8) and light grey: uninformative. LD: linkage disequilibrium is the non-random association of alleles at two or more loci, not necessarily on the same chromosome. Linkage disequilibrium describes a situation in which some combinations of alleles or genetic markers occur more or less frequently in a population than would be expected from a random formation of haplotypes from alleles based on their frequencies.