Table 2 Association results derived from linear regression between 11 9p21.3-variants and severity of disease (defined as quantitative trait) in the Italian study (N=2,908) stratified by T2D
| Â | Â | Â | Â | Â | Without T2D (N=2,343) | With T2D (N=565) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
SNP | Position | Alleles | MAF | P int | Beta | s.e. | P | P emp | Beta | s.e. | P | P emp |
rs7044859 | 22,008781 | A/T | 0.463 | 7.14E-01 | 0.011 | 0.028 | 6.94E-01 | 9.99E-01 | 0.024 | 0.054 | 6.52E-01 | 9.99E-01 |
rs10965215 | 22,019,445 | A/G | 0.435 | 6.82E-01 | 0.023 | 0.027 | 3.93E-01 | 9.27E-01 | 0.053 | 0.052 | 3.09E-01 | 8.79E-01 |
rs564398 | 22,019,547 | C/T | 0.301 | 7.66E-01 | 0.063 | 0.030 | 3.32E-02 | 1.70E-01 | 0.032 | 0.058 | 5.79E-01 | 9.96E-01 |
rs7865618 | 22,021,005 | A/G | 0.304 | - | 0.068 | 0.029 | 1.99E-02 | 1.09E-01 | 0.030 | 0.059 | 6.15E-01 | 9.98E-01 |
rs10116277 | 22,071,397 | G/T | 0.390 | 9.83E-02 | 0.054 | 0.029 | 6.01E-02 | 2.78E-01 | 0.138 | 0.067 | 4.07E-02 | 2.24E-01 |
rs4977574 | 22,088,574 | A/G | 0.398 | 9.53E-02 | 0.087 | 0.028 | 1.72E-03 | 1.17E-02 | 0.177 | 0.055 | 1.21E-03 | 9.40E-03 |
rs2383207 | 22,105,959 | A/G | 0.360 | 5.33E-02 | 0.081 | 0.029 | 5.37E-03 | 3.39E-02 | 0.198 | 0.069 | 4.52E-03 | 2.91E-02 |
rs10738610 | 22,113,766 | A/C | 0.386 | 4.28E-02 | 0.045 | 0.029 | 1.14E-01 | 4.53E-01 | 0.201 | 0.067 | 2.92E-03 | 1.99E-02 |
rs10757278 | 22,114,477 | A/G | 0.416 | 2.44E-01 | 0.019 | 0.028 | 5.01E-01 | 9.77E-01 | 0.107 | 0.054 | 4.61E-02 | 2.47E-01 |
rs1333049 | 22,115,503 | C/G | 0.421 | 6.44E-01 | 0.028 | 0.028 | 3.25E-01 | 8.60E-01 | 0.099 | 0.053 | 6.26E-02 | 3.16E-01 |
rs10811661 | 22,124,094 | C/T | 0.206 | 9.85E-01 | 0.053 | 0.035 | 1.26E-01 | 4.86E-01 | 0.051 | 0.068 | 4.56E-01 | 9.74E-01 |