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Table 1 Demographic and clinical characteristics of study population

From: T−786→C polymorphism of the endothelial nitric oxide synthase gene is associated with insulin resistance in patients with ischemic or non ischemic cardiomyopathy

 

Whole Population n =132

TT n=37

TC n=70

CC n=25

p-value TT vs CC

Mean age (mean ± SD)

65.4±10.4

64.3 ± 12.1

65.5 ± 10.0

67.1 ± 9.0

ns

Gender (male), n (%)

108 (81.8)

32 (86.5)

57 (81.4)

19 (82.6)

ns

Smoking habit, n (%)

77 (58.3)

19 (51.4)

46 (45.7)

10 (43.5)

ns

Hypercholesterolemia n (%)

73 (55.3)

14 (37.8)

46 (65.7)

11 (47.8)

ns

History of Hypertension, n (%)

45 (34.1)

9 (24.3)

25 (35.7)

9 (39.1)

< 0.05

CAD Familiarity, n (%)

56 (42.4)

19 (51.4)

46 (65.7)

10 (43.5)

ns

Obesity, n (%)

20 (15.2)

9 (2.4)

9 (1.3)

2 (0.9)

ns

DCM Etiology, n (%)

 

21 (32)

32 (48)

13 (20)

ns

IHD Etiology, n (%)

 

16 (24)

38 (58)

12 (18)

ns

LV Ejection Fraction, %

37.7 ± 7.6

38.2 ± 8.4

38.0 ± 7.1

36.4 ± 7.9

ns

LVEF<40% & NYHA Class II-III

35 (26.5)

8 (22.8)

18 (51.4)

9 (25.7)

ns

Glucose (mg/dL) ±SD

102.5 ± 23.4

95.5 ± 10.6

102.1 ± 25.3

114.2 ± 27.7

0.001

Insulin (mU/mL) ±SD

11.1 ± 7.3

9.5 ± 4.8

11.3 ± 8.3

12.9 ± 7.4

0.04

HOMA-IR ±SD

2.9 ± 2.5

2.2 ± 1.3

2.3 ± 2.8

3.9 ± 2.8

0.005

HOMA index>2.5, n (%)

58 (43.9)

11 (30.0)

32 (45.7)

15 (60)

0.008

Total Cholesterol (mg/dL) ±SD

185.7 ± 41.3

179.4 ± 34.0

188.3 ± 44.3

187.8 ± 42.4

ns

HDL-Cholesterol (mg/dL) ±SD

42.3 ± 11.9

41.2 ± 10.9

42.2 ± 13.2

44.4 ± 10.1

ns

LDL-Cholesterol (mg/dL) ±SD

118.4 ± 36.0

116.8 ± 29.1

120.2 ± 36.5

115.9 ± 44.1

ns

Triglycerides(mg/dL) ±SD

123.8 ± 82.5

107.4 ± 54.2

127.7 ± 74.2

137.4 ± 127.3

ns