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Table 1 Phenotypic characteristics of study participants

From: Methylenetetrahydrofolate reductase C677T polymorphism is associated with estimated glomerular filtration rate in hypertensive Chinese males

Variables

Male (N = 6914)

Female (N = 11900)

Age, yrs

60.2 ±7.7

59.2 ± 7.5

BMI, kg/m2

25.0 ± 3.3

26.1 ± 3.7

SBP, mmHg

166.4 ± 20.9

169.1 ± 20.8

DBP, mmHg

97.1 ± 12.3

94.0 ± 11.5

Homocysteine, μmol/L

11.2 (9.3-14.2)

9.4 (7.8-11.6)

FPG, mmol/L

5.4 (4.9-6.2)

5.5 (4.9-6.2)

TC, mmol/L

5.2 (4.5-5.9)

5.4 (4.7-6.2)

Creatinine, mmol/L

71.0 (61.7-81.7)

56.3 (48.6-66.0)

eGFR, ml/min/1.73 m2

96.4 (87.9-104.2)

97.2 (87.0-104.5)

Current smoker, %

55.3

4.8

MTHFR C677T, %

  

CC

23.9

23.5

CT

49.3

50.2

TT

26.8

26.2

  1. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, TC total cholesterol, eGFR estimated glomerular filtration rate, MTHFR methylenetetrahydrofolate reductase. Age, BMI, and blood pressures were given by mean ± sd, serum markers were given by median (Interquartile range, IQR).