Genetic model | ||||||
---|---|---|---|---|---|---|
Additive | p-value | Autosomal recessive | p-value | Autosomal dominant | p-value | |
RNLS rs2576178 | ||||||
Coronary events* | 0.963 (0.826-1.123) | 0.63 | 0.791 (0.532-1.177) | 0.25 | 1.001 (0.824-1.217) | 0.99 |
Coronary events† | 0.977 (0.820-1.163) | 0.79 | 0.798 (0.507-1.256) | 0.33 | 1.021 (0.819-1.275) | 0.85 |
Stroke* | 0.909 (0.764-1.082) | 0.28 | 0.867 (0.567-1.324) | 0.51 | 0.893 (0.717-1.111) | 0.31 |
Stroke† | 0.866 (0.710-1.056) | 0.16 | 0.663 (0.387-1.137) | 0.13 | 0.881 (0.689-1.127) | 0.31 |
Heart failure events* | 1.014 (0.808-1.273) | 0.90 | 0.887 (0.504-1.660) | 0.68 | 1.059 (0.791-1.417) | 0.70 |
Heart failure events† | 1.033 (0.800-1.335) | 0.80 | 0.801 (0.408-1.575) | 0.52 | 1.117 (0.805-1.550) | 0.51 |
Atrial fibrillation/flutter events* | 0.874 (0.746-1.024) | 0.09 | 0.852 (0.581-1.225) | 0.41 | 0.843 (0.692-1.027) | 0.09 |
Atrial fibrillation/flutter events† | 0.843 (0.706-1.006) | 0.06 | 0.859 (0.562-1.313) | 0.48 | 0.795 (0.638-0.990) | 0.04 |
RNLS rs2296545 | ||||||
Coronary events* | 0.933 (0.812-1.073) | 0.32 | 0.843 (0.653-1.089) | 0.19 | 0.964 (0.780-1.193) | 0.74 |
Coronary events† | 0.888 (0.757-1.042) | 0.15 | 0.727 (0.536-0.987) | 0.04 | 0.949 (0.745-1.209) | 0.67 |
Stroke* | 1.040 (0.892-1.213) | 0.62 | 0.982 (0.749-1.287) | 0.89 | 1.115 (0.876-1.421) | 0.38 |
Stroke† | 1.128 (0.948-1.342) | 0.18 | 1.115 (0.831-1.497) | 0.47 | 1.229 (0.928-1.626) | 0.15 |
Heart failure events* | 0.971 (0.789-1.195) | 0.78 | 0.936 (0.647-1.354) | 0.72 | 0.981 (0.714-1.348) | 0.98 |
Heart failure events† | 0.976 (0.771-1.236) | 0.84 | 0.896 (0.643-1.472) | 0.90 | 0.965 (0.674-1.381) | 0.85 |
Atrial fibrillation/flutter events* | 1.030 (0.897-1.184) | 0.67 | 1.079 (0.851-1.369) | 0.53 | 1.011 (0.815-1.253) | 0.92 |
Atrial fibrillation/flutter events† | 1.051 (0.901-1.226) | 0.53 | 1.113 (0.856-1.446) | 0.42 | 1.033 (0.814-1.312 | 0.79 |