Table 3 Logistic regression analysis of case/controls and mother/controls for DIP rs3832406 and SNP rs17080476 in all cleft samples

OR¹(95% CI²)

p- value

OR(95% CI)

p-value

OR (95% CI)

p-value

Isolated CLP

DIP Allele 1

Case-CTRL

1.1 (0.8, 1.5)

0.6159

1 (0.8, 1.3)

0.8468

1 (0.9, 1.2)

0.7022

Mother-CTRL

0.9 (0.6, 1.2)

0.3917

0.9 (0.7, 1.1)

0.4774

0.9 (0.8, 1.1)

0.3476

DIP Allele 2

Case-CTRL

1.1 (0.9, 1.4)

0.3358

0.8 (0.5, 1.4)

0.4926

1.1 (0.9, 1.3)

0.5534

Mother-CTRL

1.1 (0.9, 1.4)

0.2363

1.2 (0.7, 2)

0.5077

1.1 (0.9, 1.4)

0.2176

DIP Allele 3

Case-CTRL

0.9 (0.7, 1.1)

0.1928

1 (0.5, 2)

0.9158

0.9 (0.7, 1.1)

0.2349

Mother-CTRL

1 (0.8, 1.3)

0.9044

0.7 (0.3, 1.5)

0.3311

1 (0.8, 1.2)

0.8726

SNP

Case-CTRL

1 (0.6, 1.8)

0.9798

0.9 (0.7, 1.1)

0.1816

0.9 (0.7, 1.1)

0.2494

Mother-CTRL

1.3 (0.7, 2.5)

0.4286

0.9 (0.7, 1.1)

0.2382

0.9 (0.8, 1.1)

0.4336

Multiple CLP

DIP Allele 1

Case-CTRL

1 (0.7, 1.4)

0.9697

1 (0.8, 1.2)

0.9333

1 (0.8, 1.2)

0.9358

Mother-CTRL

0.8 (0.6, 1.2)

0.2857

0.9 (0.7, 1.2)

0.4737

0.9 (0.8, 1.1)

0.2955

DIP Allele 2

Case-CTRL

1.1 (0.9, 1.4)

0.258

0.9 (0.5, 1.6)

0.6969

1.1 (0.9, 1.3)

0.4046

Mother-CTRL

1.1 (0.9, 1.4)

0.2396

1.3 (0.8, 2.2)

0.3264

1.1 (0.9, 1.4)

0.1809

DIP Allele 3

Case-CTRL

0.9 (0.7, 1.1)

0.323

1 (0.5, 2.2)

0.9053

0.9 (0.7, 1.1)

0.3998

Mother-CTRL

1 (0.8, 1.3)

0.9303

0.7 (0.3, 1.7)

0.4316

1 (0.8, 1.2)

0.8883

SNP

Case-CTRL

1 (0.5, 1.8)

0.9538

0.9 (0.7, 1.1)

0.2786

0.9 (0.8, 1.1)

0.3381

Mother-CTRL

1.2 (0.6, 2.3)

0.5906

0.9 (0.7, 1.1)

0.2905

0.9 (0.8, 1.1)

0.4526

Isolated CPO

DIP Allele 1

Case-CTRL

1 (0.7, 1.4)

0.9498

1 (0.8, 1.2)

0.6933

1 (0.8, 1.2)

0.7915

Mother-CTRL

0.9 (0.6, 1.2)

0.3981

0.8 (0.6, 1)

0.0708

0.9 (0.7, 1)

0.0808

DIP Allele 2

Case-CTRL

1 (0.8, 1.3)

0.8703

0.5 (0.2, 1.1)

0.0749

1 (0.8, 1.2)

0.6497

Mother-CTRL

1 (0.8, 1.3)

0.7614

1.1 (0.6, 1.9)

0.798

1 (0.8, 1.3)

0.7284

DIP Allele 3

Case-CTRL

1.1 (0.9, 1.4)

0.3873

1.1 (0.5, 2.4)

0.7843

1.1 (0.9, 1.4)

0.3963

Mother-CTRL

1.3 (1, 1.7)

0.0431 ³

1.1 (0.5, 2.4)

0.7368

1.2 (1, 1.5)

0.0576

SNP

Case-CTRL

0.8 (0.4, 1.4)

0.4111

1 (0.8, 1.3)

0.7454

1 (0.8, 1.2)

1

Mother-CTRL

0.8 (0.4, 1.5)

0.4739

1 (0.8, 1.3)

0.8894

1 (0.8, 1.2)

0.7186

Multiple CPO

DIP Allele 1

Case-CTRL

1 (0.7, 1.5)

0.9335

1 (0.8, 1.3)

0.9081

1 (0.8, 1.2)

0.8998

Mother-CTRL

0.8 (0.6, 1.2)

0.3735

0.8 (0.7, 1.1)

0.2065

0.9 (0.7, 1.1)

0.1723

DIP Allele 2

Case-CTRL

1 (0.8, 1.3)

0.8253

0.5 (0.2, 1.2)

0.1285

1 (0.8, 1.2)

0.7474

Mother-CTRL

1 (0.8, 1.3)

0.824

1 (0.5, 1.9)

0.9076

1 (0.8, 1.3)

0.882

DIP Allele 3

Case-CTRL

1.1 (0.8, 1.4)

0.5704

1 (0.4, 2.5)

0.9392

1.1 (0.8, 1.4)

0.598

Mother-CTRL

1.2 (0.9, 1.6)

0.1179

1.4 (0.6, 3.1)

0.4179

1.2 (1, 1.6)

0.1044

SNP

Case-CTRL

0.9 (0.5, 1.7)

0.7393

1 (0.8, 1.3)

0.9235

1 (0.8, 1.2)

0.847

Mother-CTRL

0.7 (0.4, 1.4)

0.3247

1 (0.8, 1.3)

0.9406

1 (0.8, 1.2)

0.6925