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Genotyping of a tri-allelic polymorphism by a novel melting curve assay in MTHFD1L: an association study of nonsyndromic Cleft in Ireland

  • Stefano Minguzzi1,
  • Anne M Molloy2,
  • Kirke Peadar3,
  • James Mills4,
  • John M Scott5,
  • James Troendle4,
  • Faith Pangilinan6,
  • Lawrence Brody6 and
  • Anne Parle-McDermott1Email author
BMC Medical Genetics201213:29

DOI: 10.1186/1471-2350-13-29

Received: 19 December 2011

Accepted: 20 April 2012

Published: 20 April 2012

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
19 Dec 2011 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
3 Jan 2012 Author responded Author comments - Anne Parle-McDermott
Resubmission - Version 3
3 Jan 2012 Submitted Manuscript version 3
28 Feb 2012 Reviewed Reviewer Report - Valeria Capra
2 Mar 2012 Reviewed Reviewer Report - Pierre Zalloua
26 Mar 2012 Author responded Author comments - Anne Parle-McDermott
Resubmission - Version 4
26 Mar 2012 Submitted Manuscript version 4
2 Apr 2012 Reviewed Reviewer Report - Pierre Zalloua
Resubmission - Version 5
Submitted Manuscript version 5
20 Apr 2012 Editorially accepted
20 Apr 2012 Article published 10.1186/1471-2350-13-29

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article.. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

Nutritional Genomics Group, School of Biotechnology, Dublin City University
School of Medicine, Trinity College Dublin
Child Health Epidemiology Unit, Health Research Board
Department of Health and Human Services, Eunice Kennedy Shriver National Institute of Health
School of Immunology & Biochemistry, Trinity College Dublin
Molecular Pathogenesis Section, Genome Technology Branch, National Human Genome Research Institute