Table 2 Genetic effects from multivariate regression model.
Gene | SNP | 1 Copy of risk allele | 2 Copies of risk allele | Log additive model | |||||
|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Case/Control | OR (95% CI) | P | Case/Control | OR (95% CI) | P | OR (95% CI) | P |
NOD2 | rs2066844 | 28/20 | 2.18 (1.17-4.07) | 0.015 | 2/2 | 2.03 (0.27-15.12) | 0.49 | 2.01 (1.18-3.44) | 0.010 |
| Â | rs2066845 | 67/36 | 3.05 (1.93-4.80) | 1.14*10-6 | 6/0 | ND | - | 3.30 (2.16-5.06) | 3.92*10-8 |
| Â | rs2066847 | 61/22 | 5.03 (2.93-8.64) | 2.99*10-9 | 11/1 | 36.84 (4.55-298.29) | 0.0007 | 5.24 (3.26-8.44) | 9.18*10-12 |
IL23R | rs11209026 | 15/59 | 0.44 (0.23-0.84) | 0.013 | 0/6 | ND | - | 0.43 (0.23-0.80) | 0.0075 |
| Â | rs7517847 | 144/210 | 0.74 (0.54-1.01) | 0.06 | 20/84 | 0.24 (0.13-0.44) | 6.47*10-8 | 0.59 (0.47-0.74) | 9.20*10-6 |
IRGM | rs13361189 | 132/139 | 1.70 (1.24-2.35) | 0.0012 | 13/9 | 2.35 (0.93-5.93) | 0.072 | 1.64 (1.24-2.17) | 0.0005 |
PTGER4 | rs1373692 | 160/238 | 1.18 (0.73-1.90) | 0.50 | 167/188 | 1.75 (1.09-2.83) | 0.021 | 1.37 (1.10-1.70) | 0.0052 |