Figure 2From: Survival bias and drug interaction can attenuate cross-sectional case-control comparisons of genes with health outcomes. An example of the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism and coronary heart disease Simulated effects of statin use on the odds ratio for CHD in KIF6 719Arg carriers vs. noncarriers. Results are presented where KIF6 719Arg carriers have 50% or 25% increased risk of CHD compared with noncarriers if there is no statin use, and 0% increased risk of CHD compared with noncarriers if statins are used. Odds ratios (vertical axis) are presented for increasing percentage of statin use (horizontal axis).Back to article page