Genetic susceptibility of intervertebral disc degeneration among young Finnish adults

BMC Medical Genetics

Table 1 Candidate gene information

Nr	Gene	dbSNP¹	Location	Allele change	References
1	ADIPOQ	rs2241766	Exon 2	T/G	[51]
2	CILP	rs2073711	Exon 8	C/T	[34]
3	COL9A2	rs137853213	Exon 19	C/T	[10, 47]
4	COL9A3	rs61734651	Exon 5	C/T	[11]
5	COL11A2	rs1799907	Intron	T/A	[52, 53]
6	COL22A1	rs2292927	Exon 3	C/T	-*
7	IL1A	rs1800587	Promoter	C/T	[12, 13]
8	IL1B	rs1143634	Exon 5	C/T	[12]
9	IL1F10	rs3811058	Exon 2	T/C	[54]
10	IL6	rs1800797	Promoter	G/A	[23]
11	IL6	rs1800796	Promoter	G/C	[23]
12	IL6	rs1800795	Promoter	G/C	[23]
13	LEPR	rs1137100	Exon 4	A/G	[55]
14	LEPR	rs8179183	Exon 12	G/C	[55]
15	MMP9	rs17576	Exon 6	G/A	[56]
16	MMP10	rs470154	Intron	A/C	-*
17	SKT	rs16924573	Intron	G/A	[31]
18	THBS2	rs9406328	Intron	T/C	[56]
19	VDR	rs10735810	Exon 9	T/C	[8, 57]

ISSN: 1471-2350