Table 1 Allelic and genotypic frequencies and Hardy-Weinberg equilibrium
From: Evidence for classification of c.1852_1853AA>GC in MLH1 as a neutral variant for Lynch syndrome
| Â | Controls n = 411 | Sporadic CRC n = 373 | Familial CRC* n = 250 | Total n = 1034 |
|---|---|---|---|---|
Allele frequencies | Â | Â | Â | Â |
AA GC | 0.9866 0.0134 | 0.9879 0.0121 | 0.9860 0.0140 | 0.9869 0.0131 |
Genotype frequencies | Â | Â | Â | Â |
AA/AA AA/GC GC/GC | 0.9732 0.0268 0 | 0.9759 0.0241 0 | 0.9720 0.0280 0 | 0.9739 0.0261 0 |
HW equilibrium (p) | 0.9639 | 0.9706 | 0.9698 | 0.9448 |