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Figure 1 | BMC Medical Genetics

Figure 1

From: Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study

Figure 1

SCARB1 SNPs associated with lipid levels in an estradiol-dependent manner in postmenopausal women. Top panel - Intron/exon structure of SCARB1 isoforms, SR-BI and SR-BII; Middle two panels - P value for interaction between SCARB1 SNPs and endogenous estradiol levels for serum lipid levels in the Rancho Bernardo Study; Bottom panel - haplotype block representing associated interval (numbers are r2 values measuring pairwise linkage disequilibrium between SNPs). SNPs are ordered based on their position in the gene and from left (3') to right (5') ends of the gene. TC = total cholesterol; LDL-C = low density lipoprotein cholesterol; HDL-C = high density lipoprotein cholesterol; Trig = triglycerides; TGHDL = triglyceride:HDL-C ratio.

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BMC Medical Genetics

ISSN: 1471-2350

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