| NASH (n = 189) | Simple steatosis (n = 64) | Pvalue |
---|---|---|---|
Men/women | 99/90 | 23/41 | 0.030* |
Age (year) | 51.8 ± 15.7 (37.0; 52.5; 65.0) | 51.3 ± 13.1 (44.0; 52.5; 61.0) | 0.93 |
BMI (kg/m2) | 28.5 ± 5.6 (25.3; 28.1; 30.4) | 25.3 ± 3.5 (22.4; 24.7; 27.5) | <0.0001 |
FBS (mg/dL) | 116.7 ± 31.5 (100.0; 108.0; 124.0) | 118.0 ± 41.7 (95.8; 105.5; 122.0) | 0.27 |
HbA1c (%) | 5.9 ± 1.2 (5.1; 5.6; 6.3) | 5.8 ± 1.3 (5.0; 5.3; 6.3) | 0.22 |
Total cholesterol (mg/dL) | 210.0 ± 37.3 (183.0; 210.0; 232.0) | 218.0 ± 39.0 (189.5; 217.0; 249.0) | 0.12 |
Triglycerides (mg/dL) | 174.6 ± 103.9 (115.0; 149.0; 211.0) | 158.2 ± 80.0 (104.0; 147.0; 195.5) | 0.29 |
HDL cholesterol (mg/dL) | 51.7 ± 18.1 (41.0; 48.0; 57.3) | 54.6 ± 15.5 (44.0; 54.0; 60.5) | 0.049 |
Systolic blood pressure (mm Hg) | 127.8 ± 15.4 (118.0; 126.0; 140.0) | 124.2 ± 15.7 (111.0; 124.0; 137.0) | 0.13 |
Diastolic blood pressure (mm Hg) | 77.8 ± 11.3 (70.0; 78.0; 85.0) | 76.9 ± 11.9 (68.5; 76.0; 87.0) | 0.58 |
AST (IU/L) | 55.2 ± 31.3 (32.0; 45.0; 69.0) | 32.5 ± 16.8 (21.0; 27.0; 36.3) | <0.0001 |
ALT (IU/L) | 87.0 ± 53.2 (51.0; 76.0; 103.0) | 49.7 ± 31.1 (30.8; 41.0; 47.3) | <0.0001 |
Iron (ng/mL) | 111.7 ± 35.5 (91.0; 114.5; 134.0) | 106.1 ± 26.1 (85.5; 100.0; 123.8) | 0.087 |
Ferritin (ng/mL) | 278.1 ± 246.5 (98.0; 204.4; 379.0) | 181.2 ± 172.5 (84.0; 131.0; 175.2) | 0.0036 |
Hyaluronic acid (ng/dL) | 54.0 ± 68.5 (16.0; 32.0; 75.0) | 26.7 ± 20.5 (9.0; 23.0; 36.5) | 0.0048 |
Type IV collagen 7S (ng/dL) | 4.9 ± 1.5 (3.9; 4.7; 5.5) | 3.8 ± 0.7 (3.5; 3.7; 4.1) | <0.0001 |
Steatosis grade | 1.7 ± 0.7 (1.0; 2.0; 2.0) | 1.3 ± 0.5 (1.0; 1.0; 2.0) | <0.0001 |
Fibrosis stage | 1.4 ± 0.8 (1.0; 1.0; 2.0) | 0.1 ± 0.4 (0.0; 0.0; 0.0) | <0.0001 |