Significant association between polymorphism of the erythropoietin gene promoter and myelodysplastic syndrome

BMC Medical Genetics

Table 1 Distribution of rs1617640 EPO SNP genotype in normal control subjects and patients with various hematologic diseases

		EPO SNP Genotype				P-value (vs. normal controls)^a	P-value (vs. all leukemia samples)^a
Diagnosis		G/G	G/T	T/T	Total
Normal	n	6	41	48	95
	%	6.32	43.2	50.5			0.02
MDS	n	47	73	67	187
	%	25.1	39	35.8		<.001	<0.001
ALL	n	14	62	30	106
	%	13.2	58.5	28.3		0.03	0.61
AML	n	32	115	110	257
	%	12.5	44.8	42.8		0.1	0.21
CLL	n	11	34	52	97
	%	11.3	35.1	53.6		0.22	0.31
CML	n	44	173	136	353
	%	12.5	49	38.5		0.09	0.1
Total	n	154	498	443	1095
	%	14.1	45.5	40.5	100

ISSN: 1471-2350